Magnesium-related gene ITGAL: a key immunotherapy predictor and prognostic biomarker in pan-cancer

• Main Authors: Fengjie Lin (Author), Hanxuan Yang (Author), Zongwei Huang (Author), Ying Li (Author), Qin Ding (Author), Yunbin Ye (Author), Sufang Qiu (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2024-11-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

BackgroundIntegrin subunit alpha L (ITGAL) is crucial for activating CD8+ T cells through magnesium-mediated immune synapse formation and specific cytotoxicity. ITGAL might exert an important function in the growth and transformation of cancer.MethodsOur study comprehensively analyzed ITGAL expressi...