Several FDA-Approved Drugs Effectively Inhibit SARS-CoV-2 Infection in vitro

• Main Authors: Hua-Long Xiong (Author), Jia-Li Cao (Author), Chen-Guang Shen (Author), Jian Ma (Author), Xiao-Yang Qiao (Author), Tian-Shu Shi (Author), Sheng-Xiang Ge (Author), Hui-Ming Ye (Author), Jun Zhang (Author), Quan Yuan (Author), Tian-Ying Zhang (Author), Ning-Shao Xia (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

To identify drugs that are potentially used for the treatment of COVID-19, the potency of 1403 FDA-approved drugs were evaluated using a robust pseudovirus assay and the candidates were further confirmed by authentic SARS-CoV-2 assay. Four compounds, Clomiphene (citrate), Vortioxetine, Vortioxetine...