The Extent and Impact of Variation in ADME Genes in Sub-Saharan African Populations

• मुख्य लेखकों: Jorge E. B. da Rocha (लेखक), Houcemeddine Othman (लेखक), Gerrit Botha (लेखक), Laura Cottino (लेखक), David Twesigomwe (लेखक), Samah Ahmed (लेखक), Britt I. Drögemöller (लेखक), Faisal M. Fadlelmola (लेखक), Philip Machanick (लेखक), Mamana Mbiyavanga (लेखक), Sumir Panji (लेखक), Galen E. B. Wright (लेखक), Clement Adebamowo (लेखक), Mogomotsi Matshaba (लेखक), Michéle Ramsay (लेखक), Gustave Simo (लेखक), Martin C. Simuunza (लेखक), Caroline T. Tiemessen (लेखक), Sandra Baldwin (लेखक), Mathias Chiano (लेखक), Charles Cox (लेखक), Annette S. Gross (लेखक), Pamela Thomas (लेखक), Francisco-Javier Gamo (लेखक), Scott Hazelhurst (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Introduction: Investigating variation in genes involved in the absorption, distribution, metabolism, and excretion (ADME) of drugs are key to characterizing pharmacogenomic (PGx) relationships. ADME gene variation is relatively well characterized in European and Asian populations, but data from Afri...