Ground Calcium Carbonate as a Low Cost and Biosafety Excipient for Solubility and Dissolution Improvement of Praziquantel

• Main Authors: Ana Borrego-Sánchez (Author), Rita Sánchez-Espejo (Author), Beatrice Albertini (Author), Nadia Passerini (Author), Pilar Cerezo (Author), César Viseras (Author), C. Ignacio Sainz-Díaz (Author)
• Format: Book
• Published: MDPI AG, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Calcium carbonate is an abundant mineral with several advantages to be a successful carrier to improve oral bioavailability of poorly water-soluble drugs, such as praziquantel. Praziquantel is an antiparasitic drug classified in group II of the Biopharmaceutical Classification System hence character...