Population repeated time‐to‐event analysis of exacerbations in asthma patients: A novel approach for predicting asthma exacerbations based on biomarkers, spirometry, and diaries/questionnaires

• Main Authors: Robin J Svensson (Author), Jakob Ribbing (Author), Naoki Kotani (Author), Michael Dolton (Author), Shweta Vadhavkar (Author), Dorothy Cheung (Author), Tracy Staton (Author), David F Choy (Author), Wendy Putnam (Author), Jin Jin (Author), Nageshwar Budha (Author), Mats O. Karlsson (Author), Angelica Quartino (Author), Rui Zhu (Author)
• Format: Book
• Published: Wiley, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Identification of covariates, including biomarkers, spirometry, and diaries/questionnaires, that predict asthma exacerbations would allow better clinical predictions, shorter phase II trials and inform decisions on phase III design, and/or initiation (go/no‐go). The objective of this work w...