A simple open source bioinformatic methodology for initial exploration of GPCR ligands' agonistic/antagonistic properties

• Main Authors: Athanasios A. Panagiotopoulos (Author), Christina Papachristofi (Author), Konstantina Kalyvianaki (Author), Panagiotis Malamos (Author), Panayiotis A. Theodoropoulos (Author), George Notas (Author), Theodora Calogeropoulou (Author), Elias Castanas (Author), Marilena Kampa (Author)
• Format: Book
• Published: Wiley, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Drug development is an arduous procedure, necessitating testing the interaction of a large number of potential candidates with potential interacting (macro)molecules. Therefore, any method which could provide an initial screening of potential candidate drugs might be of interest for the acc...