Pharmacogenomics of Cardiovascular Pharmacology: Molecular Network Analysis in Pleiotropic Effects of Statin - an Experimental Elucidation of the Pharmacologic Action From Protein-Protein Interaction Analysis

• Autores principales: Masayuki Shiota (Autor), Hiromi Kusakabe (Autor), Yuko Hikita (Autor), Takafumi Nakao (Autor), Yasukatsu Izumi (Autor), Hiroshi Iwao (Autor)
• Formato: Libro
• Publicado: Elsevier, 2008-01-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

The ebb and flow of cellular life depends largely on signaling pathways and networks, which are regulated by specific protein-protein interactions. These interactions often involve assembly of large signaling complexes containing many different protein kinases, protein phosphatases, their substrates...