Differentially co‐expressed myofibre transcripts associated with abnormal myofibre proportion in chronic obstructive pulmonary disease

• Main Authors: Joe W. Chiles III (Author), Ava C. Wilson (Author), Rachel Tindal (Author), Kaleen Lavin (Author), Samuel Windham (Author), Harry B. Rossiter (Author), Richard Casaburi (Author), Anna Thalacker‐Mercer (Author), Thomas W. Buford (Author), Rakesh Patel (Author), J. Michael Wells (Author), Marcas M. Bamman (Author), Beatriz Y. Hanaoka (Author), Mark Dransfield (Author), Merry‐Lynn N. McDonald (Author)
• Format: Book
• Published: Wiley, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Skeletal muscle dysfunction is a common extrapulmonary manifestation of chronic obstructive pulmonary disease (COPD). Alterations in skeletal muscle myosin heavy chain expression, with reduced type I and increased type II myosin heavy chain expression, are associated with COPD se...