Rigid monoclonal antibodies improve detection of SARS-CoV-2 nucleocapsid protein

• Main Authors: Curtis D. Hodge (Author), Daniel. J. Rosenberg (Author), Patricia Grob (Author), Mateusz Wilamowski (Author), Andrzej Joachimiak (Author), Greg L. Hura (Author), Michal Hammel (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Monoclonal antibodies (mAbs) are the basis of treatments and diagnostics for pathogens and other biological phenomena. We conducted a structural characterization of mAbs against the N-terminal domain of nucleocapsid protein (NPNTD) from SARS-CoV-2 using small-angle X-ray scattering and transmission...