Silencing of lncRNA XIST impairs angiogenesis and exacerbates cerebral vascular injury after ischemic stroke

• Main Authors: Cong Wang (Author), Jing Dong (Author), Jinru Sun (Author), Shu Huang (Author), Feifei Wu (Author), Xinyu Zhang (Author), Defang Pang (Author), Yuan Fu (Author), Longxuan Li (Author)
• Format: Book
• Published: Elsevier, 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The aim of this study was to investigate the function and regulatory mechanism of long non-coding RNA (lncRNA) X-inactive-specific transcript (XIST) in cerebral ischemic stroke (CIS). The impact of lncRNA XIST on CIS was evaluated in acute CIS patients, middle cerebral artery occlusion (MCAO) mice,...