Silencing of lncRNA XIST impairs angiogenesis and exacerbates cerebral vascular injury after ischemic stroke

• Autori principali: Cong Wang (Autore), Jing Dong (Autore), Jinru Sun (Autore), Shu Huang (Autore), Feifei Wu (Autore), Xinyu Zhang (Autore), Defang Pang (Autore), Yuan Fu (Autore), Longxuan Li (Autore)
• Natura: Libro
• Pubblicazione: Elsevier, 2021-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

The aim of this study was to investigate the function and regulatory mechanism of long non-coding RNA (lncRNA) X-inactive-specific transcript (XIST) in cerebral ischemic stroke (CIS). The impact of lncRNA XIST on CIS was evaluated in acute CIS patients, middle cerebral artery occlusion (MCAO) mice,...