Biodistribution of adeno-associated virus serotype 9 after intrathecal and intravenous delivery in mouse

• Main Authors: Daniel J. Schuster (Author), Jaclyn A. Dykstra (Author), Maureen eRiedl (Author), Kelley eKitto (Author), Lalitha eBelur (Author), R. Scott eMcIvor (Author), Robert eElde (Author), Carolyn eFairbanks (Author), Lucy eVulchanova (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2014-06-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Adeno-associated virus serotype 9 (AAV9)-mediated gene transfer has been reported in central nervous system (CNS) and peripheral tissues. The current study compared the pattern of expression of Green Fluorescent Protein (GFP) across the mouse CNS and selected peripheral tissues after intrathecal (i....