Comprehensive Evaluation of Organotypic and Microphysiological Liver Models for Prediction of Drug-Induced Liver Injury

• Main Authors: Yitian Zhou (Author), Joanne X. Shen (Author), Volker M. Lauschke (Author)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2019-09-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Drug-induced liver injury (DILI) is a major concern for the pharmaceutical industry and constitutes one of the most important reasons for the termination of promising drug development projects. Reliable prediction of DILI liability in preclinical stages is difficult, as current experimental model sy...