Cardioprotective Roles of β-Hydroxybutyrate Against Doxorubicin Induced Cardiotoxicity

• Autores principales: Yihai Liu (Autor), Xuan Wei (Autor), Mingyue Wu (Autor), Jiamin Xu (Autor), Biao Xu (Autor), Lina Kang (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Background: β-Hydroxybutyrate (BHB) is produced by fatty acid oxidation in the liver under the fasting state and confirmed to play a cardioprotective role in ischemia and hypertensive settings. Doxorubicin (DOX) is an effective chemotherapeutic drug, but limited by serious irreversible cardiotoxicit...