Grandmaternal exercise improves metabolic health of second-generation offspring

• Main Authors: Ana B. Alves-Wagner (Author), Joji Kusuyama (Author), Pasquale Nigro (Author), Krithika Ramachandran (Author), Nathan Makarewicz (Author), Michael F. Hirshman (Author), Laurie J. Goodyear (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: A major factor in the growing world-wide epidemic of obesity and type 2 diabetes is the increased risk of transmission of metabolic disease from obese mothers to both first (F1) and second (F2) generation offspring. Fortunately, recent pre-clinical studies demonstrate that exercise before...