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Decreased Levels of GSH Are Associated with Platinum Resistance in High-Grade Serous Ovarian Cancer

High-grade serous ovarian cancer (HGSOC) is the most common and aggressive OC histotype. Although initially sensitive to standard platinum-based chemotherapy, most HGSOC patients relapse and become chemoresistant. We have previously demonstrated that platinum resistance is driven by a metabolic shif...

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Bibliographic Details
Main Authors: Daniela Criscuolo (Author), Rosario Avolio (Author), Matteo Parri (Author), Simona Romano (Author), Paola Chiarugi (Author), Danilo Swann Matassa (Author), Franca Esposito (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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