Impaired Degradation of Neutrophil Extracellular Traps: A Possible Severity Factor of Elderly Male COVID-19 Patients

• Main Authors: Nicole de Buhr (Author), Ann Christin Parplys (Author), Maria Schroeder (Author), Timo Henneck (Author), Berfin Schaumburg (Author), Stephanie Stanelle-Bertram (Author), Dominik Jarczak (Author), Axel Nierhaus (Author), Jens Hiller (Author), Sven Peine (Author), Stefan Kluge (Author), Karin Klingel (Author), Gülsah Gabriel (Author), Maren von Köckritz-Blickwede (Author)
• Format: Book
• Published: Karger Publishers, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neutrophil extracellular traps (NETs) have been described as a potential trigger of severe COVID-19. NETs are known as extracellular DNA fibers released by neutrophils in response to infection. If the host is unable to balance efficient clearance of NETs by dornases (DNases), detrimental consequence...