Lower Functional Connectivity of the Periaqueductal Gray Is Related to Negative Affect and Clinical Manifestations of Fibromyalgia

• Main Authors: Marie-Andrée Coulombe (Author), Keith St. Lawrence (Author), Dwight E. Moulin (Author), Patricia Morley-Forster (Author), Mahsa Shokouhi (Author), Warren R. Nielson (Author), Karen D. Davis (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibromyalgia (FM) syndrome is characterized by chronic widespread pain, muscle tenderness and emotional distress. Previous studies found reduced endogenous pain modulation in FM. This deficiency of pain modulation may be related to the attributes of chronic pain and other clinical symptoms experienc...