GDF10 blocks hepatic PPARγ activation to protect against diet-induced liver injury

• Main Authors: Khrystyna Platko (Author), Paul F. Lebeau (Author), Jae Hyun Byun (Author), Samantha V. Poon (Author), Emily A. Day (Author), Melissa E. MacDonald (Author), Nicholas Holzapfel (Author), Aurora Mejia-Benitez (Author), Kenneth N. Maclean (Author), Joan C. Krepinsky (Author), Richard C. Austin (Author)
• Format: Book
• Published: Elsevier, 2019-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Growth differentiation factors (GDFs) and bone-morphogenic proteins (BMPs) are members of the transforming growth factor β (TGFβ) superfamily and are known to play a central role in the growth and differentiation of developing tissues. Accumulating evidence, however, demonstrates that man...