Orally Administered <i>N</i>-Oleoyl Alanine Blocks Acute Opioid Withdrawal Induced-Conditioned Place Preference and Attenuates Somatic Withdrawal following <i>Chronic</i> Opioid Exposure in Rats
(1) Background: Intraperitoneal injections of the endogenous <i>N</i>-acyl amino acid <i>N</i>-Oleoyl alanine (OlAla) effectively reduces both the affective and somatic responses produced by opioid withdrawal in preclinical models. To increase the translational appeal of OlAl...
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MDPI AG,
2024-03-01T00:00:00Z.
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