Induced Pluripotent Stem Cell for the Study and Treatment of Sickle Cell Anemia

• Main Authors: Luiza Cunha Junqueira Reis (Author), Virgínia Picanço-Castro (Author), Bárbara Cristina Martins Fernandes Paes (Author), Olívia Ambrozini Pereira (Author), Isabela Gerdes Gyuricza (Author), Fabiano Tófoli de Araújo (Author), Mariana Morato-Marques (Author), Lílian Figueiredo Moreira (Author), Everton de Brito Oliveira Costa (Author), Tálita Pollyanna Moreira dos Santos (Author), Dimas Tadeu Covas (Author), Lygia da Veiga Pereira Carramaschi (Author), Elisa Maria de Sousa Russo (Author)
• Format: Book
• Published: Hindawi Limited, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sickle cell anemia (SCA) is a monogenic disease of high mortality, affecting millions of people worldwide. There is no broad, effective, and safe definitive treatment for SCA, so the palliative treatments are the most used. The establishment of an in vitro model allows better understanding of how th...