Gsα-dependent signaling is required for postnatal establishment of a functional β-cell mass

• Main Authors: Berta Serra-Navarro (Author), Rebeca Fernandez-Ruiz (Author), Ainhoa García-Alamán (Author), Marta Pradas-Juni (Author), Eduardo Fernandez-Rebollo (Author), Yaiza Esteban (Author), Joan Mir-Coll (Author), Julia Mathieu (Author), Stephane Dalle (Author), Max Hahn (Author), Ulf Ahlgren (Author), Lee S. Weinstein (Author), Josep Vidal (Author), Ramon Gomis (Author), Rosa Gasa (Author)
• Format: Book
• Published: Elsevier, 2021-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Early postnatal life is a critical period for the establishment of the functional β-cell mass that will sustain whole-body glucose homeostasis during the lifetime. β cells are formed from progenitors during embryonic development but undergo significant expansion in quantity and attain fun...