Autophagy Contributes to Host Immunity and Protection against Zika Virus Infection via Type I IFN Signaling

• Main Authors: Yuyi Huang (Author), Yujie Wang (Author), Shuhui Meng (Author), Zhuohang Chen (Author), Haifan Kong (Author), Ting Pan (Author), Gen Lu (Author), Xuefeng Li (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Recent studies have indicated that the Zika virus (ZIKV) has a significant impact on the fetal brain, and autophagy is contributing to host immune response and defense against virus infection. Here, we demonstrate that ZIKV infection triggered increased LC3 punctuation in mouse monocyte-macrophage c...