Transition From Full Mu Opioid Agonists to Buprenorphine in Opioid Dependent Patients-A Critical Review

• Autore principale: Michael Soyka (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-11-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Methadone, a full opioid agonist at the mu-, kappa-, and delta-receptor, and buprenorphine, a partial agonist at the mu receptor, are first-line medications in opioid maintenance treatment. Transition from methadone to buprenorphine may precipitate withdrawal, and no accepted algorithm for this proc...