Reprogramming of Trypanosoma cruzi metabolism triggered by parasite interaction with the host cell extracellular matrix.

• Main Authors: Eliciane C Mattos (Author), Gisele Canuto (Author), Nubia C Manchola (Author), Rubens D M Magalhães (Author), Thomas W M Crozier (Author), Douglas J Lamont (Author), Marina F M Tavares (Author), Walter Colli (Author), Michael A J Ferguson (Author), Maria Júlia M Alves (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Trypanosoma cruzi, the etiological agent of Chagas' disease, affects 8 million people predominantly living in socioeconomic underdeveloped areas. T. cruzi trypomastigotes (Ty), the classical infective stage, interact with the extracellular matrix (ECM), an obligatory step before invasion of alm...