Inappropriate Doses of Intravenous Polymyxin B after Renal Adjustment Lead to Treatment Failure

• Main Authors: Bahiah Ismail (Author), Mohd Nazri Shafei (Author), Azian Harun (Author), Saedah Ali (Author), Mahamarowi Omar (Author), Zakuan Zainy Deris (Author)
• Format: Book
• Published: Universidade de São Paulo, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sub-therapeutic doses, shorter duration of therapy, female gender, bacteremia, and renal impairment were among independent predictors of polymyxin B treatment failure. In this study, we found an association between inappropriate doses of polymyxin B (<15000 or >25000 unit/kg/day) and renal imp...