Trial Refresh: A Case for an Adaptive Platform Trial for Pulmonary Exacerbations of Cystic Fibrosis

• Main Authors: Andre Schultz (Author), Julie A. Marsh (Author), Benjamin R. Saville (Author), Richard Norman (Author), Peter G. Middleton (Author), Hugh W. Greville (Author), Matthew I. Bellgard (Author), Scott M. Berry (Author), Tom Snelling (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic fibrosis is a genetic disease typically characterized by progressive lung damage and premature mortality. Pulmonary exacerbations, or flare-ups of the lung disease, often require hospitalization for intensive treatment. Approximately 25% of patients with cystic fibrosis do not recover their b...