Orchestrating antigen delivery and presentation efficiency in lymph node by nanoparticle shape for immune response

• Main Authors: Hongjuan Zhao (Author), Yatong Li (Author), Beibei Zhao (Author), Cuixia Zheng (Author), Mengya Niu (Author), Qingling Song (Author), Xinxin Liu (Author), Qianhua Feng (Author), Zhenzhong Zhang (Author), Lei Wang (Author)
• Format: Book
• Published: Elsevier, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activating humoral and cellular immunity in lymph nodes (LNs) of nanoparticle-based vaccines is critical to controlling tumors. However, how the physical properties of nanovaccine carriers orchestrate antigen capture, lymphatic delivery, antigen presentation and immune response in LNs is largely unc...