Paclitaxel Inhibits Synoviocyte Migration and Inflammatory Mediator Production in Rheumatoid Arthritis

• Main Authors: Xiaochen Chen (Author), Haofeng Lin (Author), Jinyang Chen (Author), Lisheng Wu (Author), Junqing Zhu (Author), Yongnong Ye (Author), Shixian Chen (Author), Hongyan Du (Author), Juan Li (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Activated fibroblast-like synoviocytes (FLSs) play a crucial role in the pathogenesis and progression of rheumatoid arthritis (RA). It is urgent to develop new drugs that can effectively inhibit the abnormal activation of RA-FLS. In our study, the RA-FLS cell line, MH7A, and mice with collagen-induc...