Development of Paroxetine Hydrochloride Single Layer Controlled-Release Tablets Based on 3² Factorial Design

• Main Authors: Yao Yang (Author), Zhengwei Huang (Author), Xuan Zhang (Author), Jinyuan Li (Author), Ying Huang (Author), Wanxin Chen (Author), Xin Pan (Author), Chuanbin Wu (Author)
• Format: Book
• Published: MDPI AG, 2018-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Major depressive disorder (MDD) is one of the main contributors to disability and suicide mortality globally. Paroxetine hydrochloride (PHH) is the most potent antidepressant used for MDD treatment. Due to its reduced side effects PAXIL^® CR is a widely-used controlled-release...