Caesalpinia sappan reduces the stemness of breast cancer stem cells involving the elevation of intracellular reactive oxygen species

• Main Authors: Riris Istighfari Jenie (Author), Nur Dina Amalina (Author), Adam Hermawan (Author), Meiny Suzery (Author), Agung Putra (Author), Edy Meiyanto (Author)
• Format: Knjiga
• Izdano: Wolters Kluwer Medknow Publications, 2023-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

Background and purpose: Breast cancer stem cells (BCSCs) as a kind of tumor cells are able to regenerate themselves, leading to apoptosis resistance and cancer relapse. It was reported that BCSCs contain lower levels of reactive oxygen species (ROS) associated with stemness capability. Caesalpinia s...