Modulation of Transient Receptor Potential C Channel Activity by Cholesterol

• Main Authors: Rita Gutorov (Author), Maximilian Peters (Author), Ben Katz (Author), Tal Brandwine (Author), Nicolas A. Barbera (Author), Irena Levitan (Author), Baruch Minke (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Changes of cholesterol level in the plasma membrane of cells have been shown to modulate ion channel function. The proposed mechanisms underlying these modulations include association of cholesterol to a single binding site at a single channel conformation, association to a highly flexible cholester...