oxLDL Downregulates the Dendritic Cell Homing Factors CCR7 and CCL21

• Main Authors: Thomas Nickel (Author), Susanne Pfeiler (Author), Claudia Summo (Author), Reinhard Kopp (Author), Georgios Meimarakis (Author), Zeljka Sicic (Author), Marius Lambert (Author), Korbinian Lackermair (Author), Robert David (Author), Andres Beiras-Fernandez (Author), Ingo Kaczmarek (Author), Michael Weis (Author)
• Format: Book
• Published: Hindawi Limited, 2012-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction. Dendritic cells (DCs) and oxLDL play an important role in the atherosclerotic process with DCs accumulating in the plaques during plaque progression. Our aim was to investigate the role of oxLDL in the modulation of the DC homing-receptor CCR7 and endothelial-ligand CCL21. Methods and...