NOX1/NADPH oxidase is involved in the LPS-induced exacerbation of collagen-induced arthritis

• Main Authors: Misaki Matsumoto (Author), Junjie Liu (Author), Kazumi Iwata (Author), Masakazu Ibi (Author), Nozomi Asaoka (Author), Xueqing Zhang (Author), Masato Katsuyama (Author), Masaya Matsuda (Author), Takeshi Nabe (Author), Katrin Schröder (Author), Chihiro Yabe-Nishimura (Author)
• Format: Book
• Published: Elsevier, 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigate as yet an unidentified role of NOX1, a non-phagocytic isoform of the superoxide-generating NADPH oxidase, in immune responses using Nox1-knockout mice (Nox1-KO). The transcripts of NOX1 was expressed in lymphoid tissues, including the spleen, thymus, bone marrow, and inguinal lymphoid...