Photocaging of Pyridinylimidazole-Based Covalent JNK3 Inhibitors Affords Spatiotemporal Control of the Binding Affinity in Live Cells

The concept of photocaging represents a promising approach to acquire spatiotemporal control over molecular bioactivity. To apply this strategy to pyridinylimidazole-based covalent JNK3 inhibitors, we used acrylamido-<i>N</i>-(4-((4-(4-(4-fluorophenyl)-1-methyl-2-(methylthio)-1<i>H...

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Main Authors: Beate Sandra Hoffelner (Author), Stanislav Andreev (Author), Nicole Plank (Author), Pierre Koch (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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