Evaluation and clinical implications of interactions between compound Danshen dropping pill and warfarin associated with the epoxide hydrolase gene

• Main Authors: Xixi Chen (Author), Xurui Zuo (Author), Yingqiang Zhao (Author), Yuhong Huang (Author), Chunxiao Lv (Author)
• פורמט: ספר
• יצא לאור: Frontiers Media S.A., 2023-05-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

Introduction: In clinical practice, warfarin is often combined with Compound Danshen dripping pill (CDDP) for the treatment of cardiovascular diseases. However, warfarin has a narrow therapeutic index, wide interindividual variability (genetic and non-genetic factors), and is susceptible to drug-dru...