Tryptophol acetate and tyrosol acetate, small molecule metabolites identified in a probiotic mixture, inhibit hyperinflammation

• Prif Awduron: Orit Malka (Awdur), Ravit Malishev (Awdur), Marina Bersudsky (Awdur), Manikandan Rajendran (Awdur), Mathumathi Krishnamohan (Awdur), Jakeer Shaik (Awdur), Daniel A. Chamovitz (Awdur), Evgeni Tikhonov (Awdur), Eliya Sultan (Awdur), Omry Koren (Awdur), Ron N. Apte (Awdur), Benyamin Rosental (Awdur), Elena Voronov (Awdur), Raz Jelinek (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Karger Publishers, 2023-02-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Probiotic fermented foods are perceived as contributing to human health, however solid evidence for their presumptive therapeutic systemic benefits is generally lacking. Here we report that tryptophol acetate and tyrosol acetate, small molecule metabolites secreted by the probiotic milk-fermented ye...