Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice

Emerging chemo- and radiotherapy resistance exacerbated the cancer risk and necessitated novel treatment strategies. Although RNA therapeutics against pro-oncogenic genes are highly effective, tumor-specific delivery remains a barrier to the implementation of this valuable tool. In this study, we re...

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Main Authors: Chandran Sivasankar (Author), Chamith Hewawaduge (Author), Pandiyan Muthuramalingam (Author), John Hwa Lee (Author)
Format: Book
Published: Elsevier, 2023-12-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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