Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice
Emerging chemo- and radiotherapy resistance exacerbated the cancer risk and necessitated novel treatment strategies. Although RNA therapeutics against pro-oncogenic genes are highly effective, tumor-specific delivery remains a barrier to the implementation of this valuable tool. In this study, we re...
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Main Authors: | Chandran Sivasankar (Author), Chamith Hewawaduge (Author), Pandiyan Muthuramalingam (Author), John Hwa Lee (Author) |
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Format: | Book |
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Elsevier,
2023-12-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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