Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition
In the designed compounds, either a biarylamide or biarylurea moiety or an N-substituted piperazine motif was linked to position 1 of the phthalazine core. The anti-proliferative activity of the synthesised compounds revealed that eight compounds (6b, 6e, 7b, 13a, 13c, 16a, 16d and 17a) exhibited ex...
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Main Authors: | Salwa Elmeligie (Author), Asmaa M. Aboul-Magd (Author), Deena S. Lasheen (Author), Tamer M. Ibrahim (Author), Tamer M. Abdelghany (Author), Sohair M. Khojah (Author), Khaled A. M. Abouzid (Author) |
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Format: | Book |
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Taylor & Francis Group,
2019-01-01T00:00:00Z.
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Online Access: | Connect to this object online. |
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