Genetic variations in <it>APPL2 </it>are associated with overweight and obesity in a Chinese population with normal glucose tolerance

• Hlavní autoři: Jiang Shan (Autor), Fang Qichen (Autor), Yu Weihui (Autor), Zhang Rong (Autor), Hu Cheng (Autor), Dong Kun (Autor), Bao Yuqian (Autor), Wang Chen (Autor), Xiang Kunsan (Autor), Jia Weiping (Autor)
• Médium: Kniha
• Vydáno: BMC, 2012-03-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>APPL1 and APPL2 are two adaptor proteins, which can mediate adiponectin signaling via binding to N terminus of adiponectin receptors in muscle cells. Genes encoding adiponectin and adiponectin receptors contribute to insulin resistan...