Genetic variations in <it>APPL2 </it>are associated with overweight and obesity in a Chinese population with normal glucose tolerance

• Main Authors: Jiang Shan (Author), Fang Qichen (Author), Yu Weihui (Author), Zhang Rong (Author), Hu Cheng (Author), Dong Kun (Author), Bao Yuqian (Author), Wang Chen (Author), Xiang Kunsan (Author), Jia Weiping (Author)
• Format: Book
• Published: BMC, 2012-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>APPL1 and APPL2 are two adaptor proteins, which can mediate adiponectin signaling via binding to N terminus of adiponectin receptors in muscle cells. Genes encoding adiponectin and adiponectin receptors contribute to insulin resistan...