Use of High-Dose Chemotherapy in Front-Line Therapy of Infants Aged Less Than 12 Months Treated for Aggressive Brain Tumors

• Main Authors: Milena Guidi (Author), Laura Giunti (Author), Anna Maria Buccoliero (Author), Mariarita Santi (Author), Barbara Spacca (Author), Salvatore De Masi (Author), Lorenzo Genitori (Author), Iacopo Sardi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Malignant brain tumors in infants less than 12 months of age are extremely rare, and they have poor prognosis. We evaluated genetic characteristics and response rates of infants with congenital brain tumors subjected to high-dose chemotherapy and autologous stem cell transplant after g...