Changes in circulating miRNA19a-3p precede insulin resistance programmed by intra-uterine growth retardation in mice

• Main Authors: Sarah Saget (Author), Rong Cong (Author), Lyvianne Decourtye (Author), Marie-Laure Endale (Author), Laetitia Martinerie (Author), Clémence Girardet (Author), Claire Perret (Author), Maud Clemessy (Author), Patricia Leneuve (Author), Laetitia Dinard (Author), Badreddine Mohand Oumoussa (Author), Dominique Farabos (Author), Antonin Lamazière (Author), Marc Lombès (Author), Marthe Moldes (Author), Bruno Fève (Author), David Tregouet (Author), Yves Le Bouc (Author), Laurent Kappeler (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Individuals born with intrauterine growth retardation (IUGR) are more prone to cardio-metabolic diseases as adults, and environmental changes during the perinatal period have been identified as potentially crucial factors. We have studied in a preclinical model early-onset molecular alter...