Protective Effects and Mechanisms of Polyethylene Glycol Loxenatide Against Hyperglycemia and Liver Injury in db/db diabetic Mice

• Autori principali: Yu Zhang (Autore), Yufeng Li (Autore), Junjun Zhao (Autore), Cong Wang (Autore), Bin Deng (Autore), Qilin Zhang (Autore), Chen Shi (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2021-12-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Background: Type 2 diabetes mellitus (T2DM) is a metabolic disorder with insulin resistance and impaired insulin secretion that can cause complications, including liver injury. Polyethylene glycol loxenatide (PEG-Loxe), a glucagon-like peptide-1 (GLP-1) analog, is widely used to treat T2DM. However,...