Comprehensive analysis of gene expression patterns in Friedreich's ataxia fibroblasts by RNA sequencing reveals altered levels of protein synthesis factors and solute carriers

Friedreich's ataxia (FRDA) is an autosomal recessive neurodegenerative disease usually caused by large homozygous expansions of GAA repeat sequences in intron 1 of the frataxin (FXN) gene. FRDA patients homozygous for GAA expansions have low FXN mRNA and protein levels when compared with hetero...

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Main Authors: Jill Sergesketter Napierala (Author), Yanjie Li (Author), Yue Lu (Author), Kevin Lin (Author), Lauren A. Hauser (Author), David R. Lynch (Author), Marek Napierala (Author)
Format: Book
Published: The Company of Biologists, 2017-11-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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