Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice.

• Main Authors: Yifan Wu (Author), Evan Li (Author), Morgan Knight (Author), Grace Adeniyi-Ipadeola (Author), Li-Zhen Song (Author), Alan R Burns (Author), Ana Clara Gazzinelli-Guimaraes (Author), Ricardo Fujiwara (Author), Maria Elena Bottazzi (Author), Jill E Weatherhead (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2021-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ascariasis is one of the most common infections in the world and associated with significant global morbidity. Ascaris larval migration through the host's lungs is essential for larval development but leads to an exaggerated type-2 host immune response manifesting clinically as acute allergic a...