Alginate encapsulated mesoporous silica nanospheres as a sustained drug delivery system for the poorly water-soluble drug indomethacin

• Main Authors: Liang Hu (Author), Changshan Sun (Author), Aihua Song (Author), Di Chang (Author), Xin Zheng (Author), Yikun Gao (Author), Tongying Jiang (Author), Siling Wang (Author)
• Format: Book
• Published: Elsevier, 2014-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We applied a combination of inorganic mesoporous silica material, frequently used as drug carriers, and a natural organic polymer alginate (ALG), to establish a sustained drug delivery system for the poorly water-soluble drug Indomethacin (IND). Mesoporous silica nanospheres (MSNs) were synthesized...