Synthesis and Optimization of Mesoporous Silica Nanoparticles for Ruthenium Polypyridyl Drug Delivery

• Main Authors: Siti Norain Harun (Author), Haslina Ahmad (Author), Hong Ngee Lim (Author), Suet Lin Chia (Author), Martin R. Gill (Author)
• Format: Book
• Published: MDPI AG, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The ruthenium polypyridyl complex [Ru(dppz)₂PIP]²⁺ (dppz: dipyridophenazine, PIP: (2-(phenyl)-imidazo[4,5-f ][1,10]phenanthroline), or Ru-PIP, is a potential anticancer drug that acts by inhibiting DNA replication. Due to the poor dissolution of Ru-PIP i...