Cyclic Peptide-Gadolinium Nanoparticles for Enhanced Intracellular Delivery

• Main Authors: Amir Nasrolahi Shirazi (Author), Shang Eun Park (Author), Shirin Rad (Author), Luiza Baloyan (Author), Dindyal Mandal (Author), Muhammad Imran Sajid (Author), Ryley Hall (Author), Sandeep Lohan (Author), Khalid Zoghebi (Author), Keykavous Parang (Author), Rakesh Kumar Tiwari (Author)
• Format: Book
• Published: MDPI AG, 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A cyclic peptide containing one cysteine and five alternating tryptophan and arginine amino acids [(WR)₅C] was synthesized using Fmoc/tBu solid-phase methodology. The ability of the synthesized cyclic peptide to produce gadolinium nanoparticles through an in situ one-pot mixin...