Impairing the maintenance of germinative cells in Echinococcus multilocularis by targeting Aurora kinase.

• Main Authors: Zhe Cheng (Author), Fan Liu (Author), Huimin Tian (Author), Zhijian Xu (Author), Xiaoli Chai (Author), Damin Luo (Author), Yanhai Wang (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<h4>Background</h4>The tumor-like growth of the metacestode larvae of the tapeworm E. multilocularis causes human alveolar echinococcosis, a severe disease mainly affecting the liver. The germinative cells, a population of adult stem cells, are crucial for the larval growth and developme...