Cystic Fibrosis: Overview of the Current Development Trends and Innovative Therapeutic Strategies

• Main Authors: Fahad A. Almughem (Author), Ahmad M. Aldossary (Author), Essam A. Tawfik (Author), Mohammad N. Alomary (Author), Waleed S. Alharbi (Author), Mohammad Y. Alshahrani (Author), Abdullah A. Alshehri (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cystic Fibrosis (CF), an autosomal recessive genetic disease, is caused by a mutation in the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR). This mutation reduces the release of chloride ions (Cl⁻) in epithelial tissues, and hyperactivates the epi...